ALS Untangled advises against using vitamin C to treat ALS
Original source
Vitamin C (opens in a new tab)ALS Untangled advises against using vitamin C as an ALS treatment. A small clinical trial of oral vitamin C at 2,000 milligrams daily did not demonstrate benefit in people with ALS, despite earlier reports from mouse studies and two case reports suggesting possible improvement.
Why this matters
This advice applies to people considering vitamin C as a treatment for ALS. The available evidence reviewed here does not show that vitamin C improves ALS, and the appropriate beneficial dose is unclear.
Limitations and context
The evidence summary is an independent expert review published by ALS Untangled, not a new clinical study. The clinical trial was small, and the earlier mouse studies were described as flawed; the two case reports cannot establish that vitamin C caused improvement. The review does not provide enough information here to assess the trial’s design or participants in detail.