ALS Untangled does not endorse zinc supplementation as an ALS treatment
Original source
Zinc (opens in a new tab)ALS Untangled reviewed zinc as a possible treatment for amyotrophic lateral sclerosis (ALS). The review found limited clinical evidence, including case reports that showed no benefit and a very small pilot trial that suggested slower progression but did not include statistical analyses.
Why this matters
People living with ALS should not consider zinc an established treatment based on the available evidence. The review also reports that high doses without additional copper were harmful in mouse models, so zinc supplementation should not be assumed to be safe or beneficial.
Limitations and context
This is an expert review, not a new clinical trial. The clinical evidence is limited to case reports and a very small pilot trial without statistical analysis. Animal findings may not apply to people, and the review does not establish whether zinc supplementation improves ALS outcomes.