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ALS Untangled finds no evidence to support lion’s mane for ALS

Original source

Lions ManeALSUntangled · 2 January 2024

An ALS Untangled review found no studies testing lion’s mane in ALS-related cell or animal models, or in people with ALS. Although the mushroom may have properties that could theoretically be relevant to ALS, there is not enough evidence to support its use as an ALS treatment.

Why this matters

People with ALS do not currently have research evidence showing that lion’s mane treats the disease. This review does not establish a treatment benefit, and using lion’s mane should not be presented as evidence-based ALS care.

Limitations and context

This is an independent expert review, not a clinical trial or a new laboratory study. The review identifies a lack of ALS-specific evidence; potential benefits would still need to be tested in disease models and then in clinical trials.

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