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ALS Untangled says ashwagandha merits clinical testing in ALS

Original source

AshwagandhaALSUntangled · 13 February 2024

Ashwagandha appears reasonably safe and has shown promising results across several clinical models of amyotrophic lateral sclerosis (ALS), according to an ALS Untangled review. The review says one clinical trial is underway, but it does not report results from that trial.

Why this matters

Ashwagandha is being considered for formal testing in people with ALS. The available evidence does not show that it slows or reverses ALS, so this review does not change treatment decisions.

Limitations and context

This is an independent expert review, not a report of new primary research. The review also discusses self-reports and one reported reversal involving a compound containing ashwagandha; these observations are difficult to interpret because ALS progression varies naturally. Results from the ongoing trial are still needed.

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