ALSUntangled does not advise ketogenic diets as an ALS treatment
Original source
Ketogenic Diets (opens in a new tab)ALSUntangled reviewed the evidence for ketogenic diets in amyotrophic lateral sclerosis (ALS) and found no reliable evidence of benefit. Reported benefits came from one flawed preclinical study and two PatientsLikeMe participants, and were not independently verified. The review does not advise ketogenic diets for ALS because of their frequent side effects.
Why this matters
This means ketogenic diets should not be considered an established treatment for people living with ALS. A clinical trial enrolled only one person and had no control group, so it could not show whether the diet helped. ALSUntangled says another trial is needed.
Limitations and context
This is an independent expert review, not a new clinical trial. The evidence included a flawed preclinical study, unverified individual reports, and a one-person uncontrolled trial. The review called for further research and did not establish whether ketogenic diets benefit people with ALS.