ALSUntangled does not recommend fecal microbiota transplantation for ALS
Original source
Fecal Transplants (opens in a new tab)ALSUntangled reported that there were no data directly linking the fecal microbiome to ALS and no published cases of fecal microbiota transplantation (FMT) in people with ALS. It did not recommend FMT as an ALS treatment, while supporting further research into the gut microbiome and ALS.
Why this matters
People with ALS should not regard FMT as an established treatment based on this review. The proposed connection remains untested directly in ALS; research would need to first identify relevant microbiome changes and then evaluate possible interventions in controlled studies.
Limitations and context
This is an independent expert review published in 2013, not a new clinical trial or primary research study. The review described evidence from other neurological conditions as limited and indirect, and reported no direct ALS data or published ALS cases involving FMT.