ALSUntangled does not support luteolin supplements for ALS
Original source
Luteolin and Lutimax (opens in a new tab)ALSUntangled said convincing evidence that luteolin helps people with amyotrophic lateral sclerosis (ALS) is not available. It also raised safety concerns, including possible unwanted weight loss linked to a carbohydrate-deficient diet and an anecdotal report of faster disease progression. The group advised against luteolin-containing products until controlled human safety and efficacy studies are completed.
Why this matters
This applies to people with ALS considering luteolin or products such as Lutimax. The review does not establish a treatment benefit, and its recommendation means luteolin should not be viewed as a proven ALS therapy.
Limitations and context
This is an expert review published in 2011, not a new clinical trial. The source says the evidence comes from various models and that convincing human ALS data were lacking; one progression concern was anecdotal. Controlled human studies would still be needed to assess safety and effectiveness.