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Respiratory muscle training may modestly improve some breathing measures in ALS

Original source

Effects of respiratory muscle training on respiratory function in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis.J Neurol · 15 July 2026 (opens in a new tab)

Compass summarised this from the study's abstract.

Study details

Study type
Systematic review
Studied in
Human

Article

View article on the publisher's site (opens in a new tab)via the publisher — full text availability varies

A systematic review and meta-analysis of randomized trials found that respiratory muscle training was associated with small improvements in several breathing measures and in the ALS Functional Rating Scale-Revised. The effect on forced vital capacity was uncertain, and longer-term clinical benefits were not established.

Why this matters

Respiratory muscle training may be considered an individualized addition to respiratory care for some people with amyotrophic lateral sclerosis (ALS). The evidence does not show that it slows ALS or changes treatment, and the review found no reliable factors identifying who benefits most.

Limitations and context

The review included six studies, with only five contributing quantitative data. Most outcomes came from three or four small studies, and certainty ranged from moderate to very low. Larger, longer, standardised trials using outcomes important to patients are still needed.

Summarised by Compass 10 August 2026

This summary was generated by AI from the source listed above. It is not medical advice, so read the original source for anything that affects your care.

Bibliographic data from PubMed is courtesy of the U.S. National Library of Medicine. Compass does not reproduce source abstracts and may not reflect the most current record.

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