The ketogenic diet and neurodegeneration: lifeline, landmine… or something in between?
Original source
The ketogenic diet and neurodegeneration: lifeline, landmine… or something in between? (opens in a new tab)You Nutrition Clinic has a commercial interest in this subject. Compass summarises the reporting; it is not independent analysis, and it is not clinical evidence.
An expert review examines how ketogenic diets may provide an alternative fuel for brain cells in neurodegenerative diseases, including motor neurone disease (MND/ALS). It describes proposed effects on energy production and oxidative stress, based largely on biological research and laboratory or animal models.
Why this matters
The review may help explain why ketogenic approaches are being studied in MND/ALS. However, the material supplied does not show that a ketogenic diet improves symptoms, slows disease or changes treatment for people with MND/ALS.
Limitations and context
This is a sponsored expert review, not a report of a new clinical trial. The evidence described includes laboratory models and animal studies, and the supplied material does not establish a clinical benefit, an appropriate diet for people with MND/ALS or its safety for any individual. Dietary changes should not be treated as a replacement for medical care.