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Genetics and inheritance

FUS

Fused in sarcoma

A gene in which changes can cause ALS/MND, sometimes with an earlier age of onset.

What it means

The gene makes a protein involved in handling the cell's genetic messages. Changes in it are an uncommon cause of ALS/MND, and are more often found where symptoms began at a younger age.

Why you might hear it

  • It appears on genetic testing panels.
  • It is a target of some research treatments.

People who may help

Where Compass goes into this

About this explanation

These are plain explanations of words you may come across, not advice about your own situation. Where a word matters to a decision, the question pages go into it properly, and your own team is the place to take it.