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Mission & Methods
Part of ALS Untangled
Independent publisher
This describes who publishes a source, not how reliable it is.
Open source (opens in a new tab)Link checked August 2026
About this source
How ALSUntangled reviews alternative and off-label ALS treatments: the five-category Table of Evidence, the A to F grading, who assigns the grades, and where its red-flag list comes from.
Where this source is used
Used in 2 places across 1 domain.
Questions
Research & Trials
Emerging Therapies
- How do I evaluate claims about new or "miracle" treatments?
Supports this
“ALSUntangled reviews the alternative and off-label treatments people with ALS/MND are hearing about, and publishes each review with its evidence grades.”
Says why the service exists and what it covers: alternative and off-label treatments advertised for ALS on the internet, where the information is not always accurate, reviewed to help people decide about them.
ALSUntangled® systematically reviews alternative and off label treatments (AOTs) to try and help patients with ALS make more informed decisions about them.
Mission & Methods - How do I stay informed about new treatments reliably?
Supports this
“ALSUntangled reviews alternative and off-label treatments advertised for ALS, grading each one across five evidence categories, and its final grades are crowd-sourced across an international team of more than 100 clinicians and scientists from 11 countries.”
The service's own account of what it does and who does it. It reviews alternative and off-label treatments advertised for ALS, grades each one against five evidence categories, and settles the grades across a large international group of clinicians and scientists.
Final grades are crowd-sourced across an international team of more than 100 clinicians and scientists from across 11 different countries.
Mission & Methods
This is an external source. Compass links to it and describes it but does not hold rights over it. Opening it takes you to the publisher’s own site.