A review examines auditory measures as possible biomarkers in ALS and other neurodegenerative diseases
Original source
Auditory Biomarkers in Neurodegenerative Disorders: A Literature Review. (opens in a new tab)Compass summarised this from the study's abstract.
Study details
- Study type
- Review
A literature review examined auditory dysfunction and testing across amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. It reports that auditory changes may precede motor or cognitive symptoms across multiple conditions and highlights tests such as auditory brainstem responses, P300, mismatch negativity and speech-in-noise testing. The authors call for longitudinal studies to determine whether these measures can be used clinically.
Why this matters
For people with ALS, families and clinicians, this points to a possible future approach for tracking neurological changes. It does not establish that auditory testing can diagnose ALS, predict an individual’s disease course or change treatment now.
Limitations and context
This is a literature review, not a new clinical study. The source does not provide ALS-specific results, participant numbers or evidence that auditory tests improve diagnosis or treatment. The proposed clinical value still needs confirmation in longitudinal studies.