Compass is still being developed and is effectively in beta. Some content and features may be incomplete, change, or not work as expected.

Content is anchored to trusted sources where available, but Compass has not yet been clinically reviewed. It provides general information rather than medical advice.

Feedback helps us identify gaps, errors, usability problems and opportunities to improve Compass over time.

How Compass is developedGive feedback

A study identified four apathy profiles in depression and major neurocognitive disorder

Original source

Apathy phenotypes in depression and dementia: A latent profile analysis.Compr Psychiatry · 12 August 2026 (opens in a new tab)

Compass summarised this from the study's abstract.

Study details

Studied in
Human

Population inferred from the title and abstract by Compass.

Article

View article on the publisher's site (opens in a new tab)via the publisher — full text availability varies

Researchers analysed apathy patterns in 328 people with major depressive disorder or major neurocognitive disorder. They identified four profiles, including global, mild, minimal and executive apathy.【S1】

Why this matters

The findings may help clinicians describe apathy more precisely in these populations. The study does not establish effects on ALS or motor neurone disease treatment, and its use of “MND” refers to major neurocognitive disorder, not motor neurone disease.【S1】

Limitations and context

This was one observational study using latent profile analysis in 328 participants from major depressive disorder and major neurocognitive disorder groups. The source does not report an ALS or motor neurone disease population, treatment outcomes or proof that the profiles improve diagnosis or care.【S1】

Summarised by Compass 18 August 2026

This summary was generated by AI from the source listed above. It is not medical advice, so read the original source for anything that affects your care.

Bibliographic data from PubMed is courtesy of the U.S. National Library of Medicine. Compass does not reproduce source abstracts and may not reflect the most current record.

Relevant to you?