At-home vital capacity measurements closely matched clinic measurements in an ALS trial
Original source
At-Home Versus in-Clinic Vital Capacity Measurement: Insights From the HEALEY ALS Platform Trial. (opens in a new tab)Compass summarised this from the study's abstract.
Study details
- Studied in
- Human
At-home and in-clinic vital capacity measurements were well correlated in 233 people with amyotrophic lateral sclerosis (ALS) taking part in the HEALEY ALS Platform Trial. At-home measurements also tracked changes over time and showed a similar ability to predict survival, although they declined faster than clinic measurements.
Why this matters
The findings support coached, video-supervised at-home vital capacity monitoring in ALS research and potentially reduce the need for clinic visits. This study assessed measurement agreement and prediction, not a treatment benefit, so it does not by itself change ALS treatment.
Limitations and context
The analysis included 233 trial participants with paired measurements over about one year. At-home testing was coached by live videoconference and centrally reviewed, so the findings may not apply to unsupervised home testing. The study compared measurements rather than testing whether home monitoring improves care or outcomes.