Cracking the genetic code in MND
Original source
Cracking the genetic code in MND (opens in a new tab)Related topics
A study using Project MinE data found that 6% of people with motor neurone disease (MND) carried variants in more than one MND-associated gene. These people had shorter survival and faster progression, particularly when one variant was in C9orf72. The study found no difference in age at disease onset.
Why this matters
The findings suggest that assessing several MND-related genes together may improve understanding of prognosis. This is a genetic research finding and does not currently change treatment for people with MND.
Limitations and context
The evidence is described in an organisation’s blog about research presented at an international symposium, not in a primary research paper supplied here. The source does not provide the study’s full sample size, methods, statistical results or peer-review status. It also does not establish that genetic testing based on these findings improves outcomes or should be used to guide treatment.