HumanHighly relevant to this reader view.
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Trials & Treatments
All Trials & Treatments stories- ReportingSomewhat relevant to this reader view.
ALS Nexus 2026: Experimental therapy shows early promise in SOD1-ALS
- HumanMouseHighly relevant to this reader view.
JP1 improved movement and survival in ALS model mice by targeting oxidative stress and autophagy
- ReportingHighly relevant to this reader view.
Tiziana Life Sciences to present Phase 2a BANYAN trial data at ALS Nexus 2026
- ReviewHumanAnimalHighly relevant to this reader view.
Review outlines why ALS trials fail and how more personalised treatment could help
- HumanHighly relevant to this reader view.
New laboratory methods measure a proposed ALS drug combination
- ReviewHumanAnimalHighly relevant to this reader view.
Mesenchymal stem cell treatments appear generally safe, but benefits in ALS remain uncertain
- Highly relevant to this reader view.
A severe hypersensitivity reaction was reported during tofersen therapy in ALS
- HumanMouseUpdatedSomewhat relevant to this reader view.
ALS Untangled does not recommend ivermectin for ALS
- Results postedPhase 1UpdatedHighly relevant to this reader view.
Results posted for phase 1 trial of Autologous T-regulatory lymphocytes
Research
All Research stories- Case reportHumanHighly relevant to this reader view.
A VCP variant was linked to an unusual pattern of tau buildup in the nervous system
- HumanHighly relevant to this reader view.
Study finds racial and ethnic differences in ALS progression and survival among U.S. Veterans
- HumanMouseHighly relevant to this reader view.
A drug candidate that blocks BAX protected motor neurons in laboratory studies
- Highly relevant to this reader view.
Engineered nanopores detect proteins linked to ALS and other diseases
- HumanHighly relevant to this reader view.
ATXN2-related disease may sometimes follow a recessive inheritance pattern
- HumanHighly relevant to this reader view.
A German registry study found that 12% of people with ALS lived at least 10 years after symptoms began
- HumanHighly relevant to this reader view.
Butyrate reduced ALS-linked protein clumps and improved movement in worms and cells
- HumanMouseHighly relevant to this reader view.
Engineered delivery system clears harmful Tau and TDP-43 in disease models
- ReviewHumanAnimalHighly relevant to this reader view.
A review outlines how immune responses might guide more precise ALS treatments
- HumanHighly relevant to this reader view.
ALS linked to C9orf72 repeat expansion showed greater difficulty interpreting thoughts and emotions
Care & Living
All Care & Living stories- Observational studyHumanSomewhat relevant to this reader view.
Feeding-tube placement was feasible and safe in people with advanced ALS
- ReportingHighly relevant to this reader view.
ALS Nexus 2026: Implantable device decodes patients’ brain signals
- HumanHighly relevant to this reader view.
Virtual care could remain part of neuromuscular care, but more evidence is needed
- HumanSomewhat relevant to this reader view.
Documented end-of-life decisions were linked to more comfort-focused care in a neurological ward
- HumanHighly relevant to this reader view.
Rural residence was linked to more MAiD referrals in a Canadian ALS clinic study
- HumanHighly relevant to this reader view.
U.S. registry study links multidisciplinary ALS clinic attendance with more specialized care
- HumanHighly relevant to this reader view.
Speech severity affects how much intelligibility must change to indicate a real difference
- HumanSomewhat relevant to this reader view.
A two-center study identified factors linked to poorer survival after gastrostomy in ALS
- Somewhat relevant to this reader view.
A study reports longer hospital stays and more long-term complications after emergency tracheostomy in ALS
- HumanSomewhat relevant to this reader view.
Advance care planning was documented for about half of Italian ALS patients
Community & Public Life
All Community & Public Life stories- AdvocacyHighly relevant to this reader view.
The NIH NeuroBioBank (NBB) is a federated program supporting seven brain banks across the United States.
- News & Culture ReportingBackground to this reader view.
'Pretty remarkable' man living with MND for 29 years after diagnosis
- AdvocacySomewhat relevant to this reader view.
Meet Beth: Introducing our new Research Engagement and Involvement Manager
- News & Culture ReportingUpdatedBackground to this reader view.
Sandra Bullock speaks publicly about partner Bryan Randall’s private ALS battle
- Advocacy ReportingBackground to this reader view.
ALS Nexus 2026: It ‘takes us all’ to change the future of ALS
- Community & Stories DiscussionSomewhat relevant to this reader view.
Monthly MEGATHREAD: Research and Feedback Outreach
- AdvocacyHumanHighly relevant to this reader view.
Assisted living regulations were linked to higher hospice quality ratings
- Advocacy ReportingMainly relevant to the United States.Highly relevant to this reader view.
House passes bill to renew federal law for ALS research and care
- AdvocacyCommentaryHumanSomewhat relevant to this reader view.
A journal article warns that consumer AI can misdiagnose ALS
- AdvocacyHumanHighly relevant to this reader view.
Moral distress is common among European healthcare professionals working in motor neuron disease
From Curalysis
- Clinical trials need to leave the clinic2 months ago
- There’s No Map for This5 months ago
- On the Inside of a Clinical Trial7 months ago
Summarised by Compass using AI from the source material. These are not medical advice. Always read the original source.